Formation of Cyclopentanes and Cyclopropanes through Alkylation of Benzylic Anions using Ethers, Thioethers and Alcohols as substrates under Grubbs-Stoltz (Et 3 SiH/KO t Bu) conditions.

Key Points

• The aim is to explore the formation of cyclopentanes and cyclopropanes through the alkylation of benzylic anions using various substrates.
• Used the Grubbs-Stoltz reagent (KO t Bu + Et 3 SiH)
• Conducted reactions in THF solvent
• Focused on double-alkylation reactions with diarylmethanes
• Successfully synthesized diarylcyclopentanes through double-alkylation
• Formation of cyclopentanes involved unprecedented reaction pathways
• Demonstrated utility of ethers, thioethers, and alcohols as substrates