What question did this study set out to answer?

The research aims to evaluate the safety and effectiveness of targeted microwave ablation for localized prostate cancer.

March 13, 2026

Targeted microwave ablation of localised prostate cancer ( VIOLETTE trial ): a prospective multicentre study

Key Points

The research aims to evaluate the safety and effectiveness of targeted microwave ablation for localized prostate cancer.
Conducted as a prospective multicentre trial
Utilized OBT Fusion technology for microwave ablation
Focused on patients with localized intermediate-risk prostate cancer
Monitored patients for 12 months post-treatment
Achieved primary endpoint of the trial
81% of patients remained free of in-field clinically significant prostate cancer (csPCa) after 12 months

Abstract

Targeted microwave ablation using OBT Fusion technology appears to be a safe and effective focal therapy procedure for localised intermediate-risk PCa. The VIOLETTE trial achieved its primary endpoint, with 81% patients free of in-field csPCa at 12 months.

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