What question did this study set out to answer?

This case aims to highlight the unusual presentation of colorectal cancer during pregnancy and the role of imaging in diagnosis.

March 13, 2026Indian Journal of Nuclear Medicine0 citationsOpen Access

Unusual Presentation of Colonic Adenocarcinoma at Third Trimester with Possible Underlying Familial Adenomatous Polyposis Detected on ( 18 F)-FDG PET-CT

GGGeet GargBhabha Atomic Research Centre PVPriyanka VermaBhabha Atomic Research Centre SBSANDIP BASUBhabha Atomic Research Centre

Key Points

This case aims to highlight the unusual presentation of colorectal cancer during pregnancy and the role of imaging in diagnosis.
Reported a case involving a 30-year-old female post-delivery.
Used 18F-FDG PET-CT to analyze liver lesions.
Identified colonic lesions and assessed disease extent.
Detected multiple polypoidal lesions in the colon via PET-CT.
Found hypodense lesions in the liver.
Observed a tumor sink effect linked to colonic adenocarcinoma.

Abstract

Colorectal carcinoma during pregnancy is a rare entity, often presenting with nonspecific symptoms that can be misattributed to physiological changes associated with pregnancy. We present the case of a 30-year-old female with a history of spontaneous preterm delivery, in whom postpartum ultrasonography revealed multiple hypoechoic lesions in the liver. 18 F-fluorodeoxyglucose ( 18 F-FDG) positron emission tomography/computed tomography (PET/CT) done to characterize the liver lesions, revealed multiple FDG concentrating polypoidal lesions in the colon, multiple hypodense liver lesions and tumor sink effect. This case highlights the atypical presentation of colorectal carcinoma during pregnancy and emphasizes the pivotal role of 18 F-FDG PET/CT in delineating disease extent and identifying metastatic sites.

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