A Review on Dry Emulsion: Formulation and Evaluation

The goal of the dry emulsion formulation is to decrease the adverse effects of drugs and increase their bioavailability. Because they are formulations that are both physically and microbiologically stable, dry emulsions are appealing. For lipophilic and poorly soluble medicinal compounds, they offer a possible oral drug administration method. Liquid o/w emulsions with a solid carrier in the aqueous phase are dried to create dry emulsion. Spray drying, lyophilization, and rotary evaporation are methods for creating dry emulsions. Lactose, mannitol, and maltodextrins are organic filters used in the preparation of dry emulsion. The oils employed in this study are olive oil, sesame oil, and peppermint oil. Pre-formulation experiments revealed that HPMC was the ideal gum for making dry emulsion, while mannitol was the organic filler. It was discovered through observations that the drug’s stability and bioavailability were improved by manufacturing it as a dry emulsion. Keywords: Dry emulsion, solid carriers, lyophilization