The emerging role of magnesium in peripheral nerve regeneration: biomaterial design, mechanistic basis, and translational barriers

Key Points

• The research aims to explore the role of magnesium in supporting peripheral nerve regeneration through specific biomaterials.
• Identified mechanisms by which magnesium influences nerve repair.
• Analyzed the effects of magnesium on Schwann cell activity and axonal growth.
• Evaluated the role of magnesium in modulating neuroinflammation and angiogenesis.
• Mg-based biomaterials provide mechanical support for nerve repairs.
• Promote significant axonal growth and Schwann cell activity.
• Show enhanced angiogenesis and neuroinflammation modulation.