Standard resuscitation relies on CPR and adrenaline, but microvascular occlusion limits efficacy. GPV (Glossopharyngeal-Vagal) stimulation is proposed as a microcirculation-preserving alternative. We develop a computational model integrating Poiseuille flow, Murray vascular branching, microthrombi formation, and the Ibaguner Fractal Operator (IFO) to compare coronary perfusion under CPR, adrenaline, and GPV stimulation. Histological occlusion data are used for calibration. The model predicts significantly higher effective coronary flow and lower mi-crovascular occlusion under GPV stimulation compared to CPR and adrenaline. These findings suggest GPV may preserve microcirculation during cardiac arrest resuscitation and warrants further experimental study.
Sinan Ibaguner (Tue,) studied this question.