Chronic inhalation exposure to 0.5 ppm of 2-ethyl-1-hexanol induces histopathological changes in olfactory, respiratory, and skin tissue of mice
Key Points
The aim is to investigate the effects of chronic inhalation exposure to 0.5 ppm of 2-ethyl-1-hexanol on mouse tissue.
Conducted inhalation exposure on mice to assess tissue changes.
Evaluated histopathological alterations in olfactory, respiratory, and skin tissues.
Analyzed inflammation levels in the olfactory epithelium, olfactory bulb, bronchi, and alveoli.
Observed inflammation in olfactory epithelium and bulb.
Detected changes in bronchi and alveoli tissues.
Histopathological alterations imply significant impact on respiratory functions.
Abstract
Chronic inhalation exposure at as low as 0.5 ppm caused inflammation in the OE, OB, segmental bronchi, and alveoli, and affected the target area of OB neurons.
Chronic inhalation exposure to 0.5 ppm of 2-ethyl-1-hexanol induces histopathological changes in olfactory, respiratory, and skin tissue of mice | Synapse