What question did this study set out to answer?

To characterize complete genomes of E. coli isolates that possess the eatA gene, a marker of virulence.

March 25, 2026Open Access

Complete genomes of Escherichia coli isolates encoding the EatA autotransporter from pediatric sources

Q: What does this research mean for the field?

Twelve complete genomes of Escherichia coli isolates from pediatric subjects contain the virulence-associated enterotoxigenic E. coli autotransporter A gene (eatA). Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

Key Points

To characterize complete genomes of E. coli isolates that possess the eatA gene, a marker of virulence.
Isolated 12 E. coli samples from pediatric subjects in a multicenter study.
Sequenced the complete genomes of the isolates.
Analyzed the presence of the eatA gene.
All isolates contained the virulence-associated eatA gene.
Characterization revealed distinct genomic features across the isolates.
These findings provide insights into the genetic background related to virulence in E. coli.

Abstract

Virulence in Escherichia coli is multifactorial, with additional virulence factors continuously being examined and characterized. We describe the complete genomes of 12 E. coli isolates obtained from subjects enrolled in the Global Enteric Multicenter Study, each containing the virulence-associated enterotoxigenic E. coli autotransporter A gene (eatA).

Complete genomes of Escherichia coli isolates encoding the EatA autotransporter from pediatric sources

Key Points

Abstract

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