Construct a label-free COF/PTh/MB electrochemical immunosensor for the detection of CA-125

Key Points

• The aim is to develop a label-free electrochemical immunosensor for the detection of CA-125, a tumor marker for ovarian cancer.
• Developed a label-free electrochemical immunosensor using COF/PTh/MB nanocomposite.
• Utilized electrochemical techniques for the detection of CA-125 levels.
• Optimized sensor parameters to enhance sensitivity and specificity.
• Demonstrated the sensor's capacity for rapid and sensitive detection of CA-125.
• Achieved significant sensitivity towards CA-125 with low detection limits.