SYSTEMATIC REVIEWefficacy, primarily attributed to the active compound allicin, positions it as a promising candidate for inclusion in pulpectomy procedures. 6Allicin's potency against a spectrum of microorganisms not only offers an effective alternative to synthetic agents but also addresses concerns related to microbial resistance and the adverse effects associated with conventional irrigants. 7M. citrifolia, commonly known as noni, contributes another layer to the exploration of herbal intracanal irrigants.With a IntroductIonPulpectomy, a crucial procedure in pediatric endodontics, involves the thorough extraction of infected pulp tissue and serves as a standard intervention for addressing pulp pathologies in primary molars. 1 The success of pulpectomy hinges not only on the meticulous debridement and disinfection of the root canal system but also on the judicious selection of intracanal irrigants employed during the procedure.In recent years, the landscape of pediatric endodontics has undergone a dynamic transformation, fueled by the pursuit of safer, more sustainable, and biocompatible alternatives. 2Traditional endodontic irrigants have predominantly featured synthetic chemicals.However, a discernible shift has transpired in recent times, marked by a burgeoning interest in exploring alternative, natural substances that offer therapeutic benefits. 3his departure from synthetic agents to herbal irrigants is motivated by apprehensions regarding potential side effects and the environmental impact associated with conventional chemical agents. 4Among the diverse array of herbal options, noteworthy herbs such as Allium sativum (garlic), Morinda citrifolia (noni), Salvadora persica (miswak), and Tulsi have gained prominence owing to their distinguished antimicrobial, anti-inflammatory, and antioxidant properties. 5arlic, scientifically known as A. sativum, has been a stalwart in traditional medicine across various cultures.Its antimicrobial
Raj et al. (Fri,) studied this question.