Pineal glioblastoma: a case series and updated literature review

Key Points

• To characterize pineal glioblastoma cases based on the 2021 WHO classification and assess outcome variability.
• Defined a cohort of pineal glioblastoma cases under the updated WHO classification.
• Performed molecular and epigenetic stratifications to analyze patient outcomes.
• Reviewed existing literature for a comprehensive understanding of treatment implications.
• Outcomes of pineal glioblastoma cases varied significantly across the cohort.
• Data supported the need for tailored prognostication strategies.
• Molecular stratification indicated potential pathways for improved therapeutic decisions.