environmental domain scores, but higher social domain scores.Overall QoL did not differ significantly between HD + HDF and PD.QoL showed no association with age, sex, BMI, or major comorbidities, though thyroid disorders and higher phosphorus and TSH levels correlated negatively with QoL.Among in-hospital patients, dialysis frequency had no effect on QoL, but HDF patients had significantly better domain and total scores than HD patients.On comparison across modalities, HD patients demonstrated the lowest QoL in all domains except social, where HDF patients had the highest scores.Conclusion: Maintenance dialysis significantly impairs patients' quality of life.Among modalities, home peritoneal dialysis and in-hospital hemodiafiltration were associated with better QoL than conventional hemodialysis.These findings highlight the need to promote patientcentric, home-based dialysis options and optimize comorbidity management to improve overall well-being in Indian dialysis populations.Further studies with larger sample sizes are recommended to explore various dimensions of the problem and interrelationships of different factors affecting quality of life.I have no potential conflict of interest to disclose.I did not use generative AI and AI-assisted technologies in the writing process.
Castillo-Babaran et al. (Wed,) studied this question.