The study aims to investigate the causal relationship between gut microbiota, their metabolites, and the risk of diffuse large B-cell lymphoma (DLBCL).
Conducted a Mendelian randomization analysis to explore causal links.
Identified specific gut microbial taxa and metabolites.
Analyzed data reflecting the risk of DLBCL associated with gut microbiota.
Found evidence that certain gut microbial taxa may increase the risk of DLBCL.
Identified specific metabolites derived from gut microbiota that could influence the disease risk.
Abstract
This MR study provides evidence that specific gut microbial taxa and microbiota-derived metabolites may causally influence the risk of DLBCL.