What question did this study set out to answer?

This research aims to investigate the relationship between placental pathology and periventricular leukomalacia (PVL) in preterm infants.

March 29, 2026

Periventricular Leukomalacia in a Preterm Cohort: Associations With Placental Pathology

Key Points

This research aims to investigate the relationship between placental pathology and periventricular leukomalacia (PVL) in preterm infants.
Analyzed a large cohort of preterm infants born weighing less than 1500 grams.
Evaluated placental histology for chorioamnionitis.
Correlated findings between placental inflammation and incidents of PVL in infants.
Demonstrated a strong association between histologic chorioamnionitis and the occurrence of PVL.
Highlighted that infants with placental inflammation showed higher rates of brain injury.

Abstract

In a large cohort of preterm infants, we demonstrate a strong association between AI in the placenta (histologic chorioamnionitis) and PVL in infants born <1500 g.

اسأل الذكاء الاصطناعي

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