Cardiac glycosides, including Deslanoside, are widely used for ventricular rate control in atrial fibrillation (AF). We report a 73-year-old man with paroxysmal AF and no structural heart disease who developed left posterior fascicular ventricular tachycardia (LPFVT) shortly after intravenous Deslanoside administration. A close temporal relationship was observed between drug administration and arrhythmia onset, with a shorter latency following a second intravenous dose. These findings suggest that Deslanoside may have facilitated LPFVT. This case highlights that cardiac glycosides, while effective for rate control, may occasionally precipitate Purkinje-related ventricular tachycardia.
Wenjun et al. (Sat,) studied this question.