ent -Pimarane diterpenoids from the aerial parts of Sigesbeckia pubescens and their myocardial protective activity

Key Points

• To isolate and characterize new ent -pimarane diterpenoids from Sigesbeckia pubescens and evaluate their myocardial protective effects.
• Isolation of diterpenoids from the aerial parts of Sigesbeckia pubescens.
• Characterization of compounds 1–8 and comparison with known compounds 9–11.
• Isolated eight new ent -pimarane diterpenoids alongside three known ones.
• Demonstrated potential myocardial protective activity of the isolated compounds.