Baseline right ventricular SV/RVESV >0.395 in patients undergoing tricuspid transcatheter edge-to-edge repair was associated with higher 2-year survival compared to ≤0.395 (90.4% vs. 68.3%).
Does baseline SV/RVESV predict 2-year survival in patients undergoing T-TEER for severe TR?
Baseline 3D echocardiography-derived RV forward SV/RVESV >0.395 is associated with significantly better 2-year survival in patients undergoing T-TEER for severe TR.
Absolute Event Rate: 0% vs 0%
Abstract Background The ratio of right ventricular (RV) forward stroke volume (SV) to end-systolic volume (SV/RVESV), derived from three-dimensional (3D) echocardiography, has emerged as a noninvasive surrogate of RV-pulmonary artery (PA) coupling and is prognostically relevant in conservatively managed tricuspid regurgitation (TR). However, its role in patients undergoing tricuspid valve transcatheter edge-to-edge repair (T-TEER) remains unknown. Purpose To evaluate the prognostic value of SV/RVESV in patients undergoing T-TEER for severe TR. Methods This single-center retrospective study included consecutive patients undergoing T-TEER (2020–2023) with complete 3D RV volumetric data at baseline and discharge. The primary endpoint was 2-year survival. Results Seventy-five patients (median age 81 years; 65% female; 72% NYHA III/IV) had a median baseline SV/RVESV of 0.422 (0.353–0.521), increasing to 0.478 (0.359–0.592) at discharge (P=0.034). A baseline SV/RVESV 0.395 (High) was associated with superior 2-year survival compared with ≤0.395 (Low) (90.4% 95%CI: 80.4–100% vs. 68.3% 95%CI: 51.8–90.2%; P=0.021). Patients with low SV/RVESV had larger RV volumes, reduced RV function, and more advanced TR. Acute increases in SV/RVESV were confined to patients with residual TR ≤II, whereas no significant changes occurred in those with residual TR II. Residual TR ≤II rates were similar between groups. Conclusion In patients undergoing T-TEER, baseline RV forward SV/RVESV was strongly associated with long-term survival. High SV/RVESV patients had less advanced RV remodeling, underscoring its potential for preprocedural risk stratification and timely intervention.
Iliadis et al. (Sun,) reported a other. Baseline right ventricular SV/RVESV >0.395 in patients undergoing tricuspid transcatheter edge-to-edge repair was associated with higher 2-year survival compared to ≤0.395 (90.4% vs. 68.3%).