This case illustrates a rare and aggressive presentation of extramedullary AML with monocytic differentiation and high-risk cytogenetics in a young postpartum patient, initially mimicking a localized odontogenic infection. The delayed diagnosis underscores the complexity of recognizing extramedullary leukaemia, particularly when early hematologic abnormalities are subtle or absent. The presence of a t(10;11) translocation and the subsequent development of leukaemia cutis following induction therapy highlight the aggressive biologic behaviour of this disease and reinforce the importance of heightened clinical suspicion, prompt tissue diagnosis, and vigilant surveillance for extramedullary relapse, which may require intensified therapeutic approaches.
Pustake et al. (Thu,) studied this question.