Background: Organophosphorus (OP) is reachable pesticide which has a high morbidity. There is limited information available on acute poisoning in the study area. Aim of the Study: To study the clinical profile, laboratory profile and outcome of organophosphorus poisoning at tertiary care hospital. Materials and Methods: A total of 100 individuals with organo-phosphorus poisoning were enrolled in this study and were categorized (mild, moderate, and severe poisoning groups) based on peradeniya organophosphorus poisoning (POP) score. Their serum cholinesterase (SChE) levels at the time of admission were sent and categorized into three groups. The POP score, SChE levels were analyzed to find their association with mortality, ventilator support, and duration of hospital stay. Results: Of 100 patients with organophosphorus (OP) poisoning, a majority of 36% subjects were aged between 21 and 30 years (66% males and 34% females), with a male-to-female ratio of 1.9:1. Chlorpyriphos (59%) was the most common type of poisoning followed by dimethoate (16%). A majority (46%) had mild, 38% had moderate, and 16% had severe poisoning. The overall mortality was 14%, mortality in patients requiring ventilator was 21.5% and the case fatality rates for were high in severe poisoning (62.5%). Conclusion: A higher POP score and a significant decrease in SCh-E levels were associated with increase in the duration of hospital stay, severity of poisoning, need of ventilator, and poor outcome.
Patil et al. (Thu,) studied this question.