Progressive adoption of pulsed field ablation for atrial fibrillation is projected to generate €11.7 million in cumulative savings over 5 years for the Italian National Health Service.
Does the progressive introduction of pulsed field ablation reduce healthcare costs compared to cryoballoon and laser ablation in patients with atrial fibrillation?
The progressive integration of pulsed field ablation into routine atrial fibrillation care in Italy is projected to generate €11.7 million in savings over 5 years, primarily driven by reduced procedural costs and fewer recurrences.
Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia, with a higher prevalence due to the ageing of the population. Traditional ablation techniques, such as cryoballoon ablation (CB) and laser ablation (LA), are widely used but may be associated with longer procedure times and a risk of collateral tissue injury. Pulsed field ablation (PFA) is an emerging non-thermal technology that uses electroporation, with early evidence suggesting a favourable safety profile and improved procedural efficiency. This study assessed the budget impact of the introduction of PFA within the Italian National Health Service (NHS) compared with current CB and LA practice, estimating short-term differences in healthcare costs to support resource allocation decisions. A 5-year budget impact model compared two scenarios: current clinical practice (CB and LA) and a progressive uptake of PFA, increasing from 20% in 2025 to 67.2% in 2029. The analysis included direct medical costs: device acquisition, staff time, procedural resources, complications and repeat interventions. The population and treatment assumptions were based on national and regional data from Italy. The analysis was conducted from the perspective of the NHS. A deterministic sensitivity analysis was performed to assess the robustness of the results. The introduction of PFA resulted in cumulative cost savings of €11.7 million over 5 years. In the current scenario, costs increased from €36.2 million to €38.1 million. In contrast, costs in the PFA scenario decreased from €35.8 million to €33.2 million. The main savings came from reduced staff and procedural costs (€7.6 million), fewer recurrences (€5.9 million) and lower costs related to complication (€1.5 million). Sensitivity analysis confirmed the robustness of the results, with device cost, CB pricing and procedure time identified as the most influential parameters. Our study suggests that the progressive integration of PFA into routine AF care within the Italian NHS could generate meaningful cost savings while maintaining clinical outcomes.
Fiumalbi et al. (Wed,) conducted a other in Atrial Fibrillation. Pulsed field ablation (PFA) vs. Cryoballoon ablation (CB) and Laser ablation (LA) was evaluated on Cumulative budget impact (direct medical costs). Progressive adoption of pulsed field ablation for atrial fibrillation is projected to generate €11.7 million in cumulative savings over 5 years for the Italian National Health Service.