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Diagnostic challenges in Flaviviridae infections: first human case of Usutu virus aseptic meningitis in an immunocompetent subject in Italy. | Synapse
April 4, 2026
Open Access
Diagnostic challenges in Flaviviridae infections: first human case of Usutu virus aseptic meningitis in an immunocompetent subject in Italy.
GT
Giacomo Trillocco
GG
Gabriele Giuliano
GA
Giulia Alessandri
University of Siena
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Key Points
This research aims to highlight the diagnostic complexities of flaviviridae infections, especially Usutu virus.
Case presentation of an immunocompetent individual
Clinical evaluation and diagnostic testing
Analysis of symptoms and laboratory results
First reported human case of Usutu virus causing aseptic meningitis
Patient presented with typical symptoms of viral meningitis
Diagnostic challenges included differentiating from other viral infections
Abstract
subject in Italy.
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Trillocco et al. (Wed,) studied this question.
synapsesocial.com/papers/69d0ae68659487ece0fa45ba
https://doi.org/https://doi.org/10.1016/j.ijid.2026.108667