First clinical application of autologous fibrin sealant Vivostat for neurosurgery in Kazakhstan and Central Asia

Key Points

• This research aims to evaluate the clinical efficacy and safety of autologous fibrin sealant Vivostat in neurosurgery.
• Conducted first clinical application in Kazakhstan and Central Asia
• Evaluated efficacy for dural sealing and skull base reconstruction
• Assessed postoperative outcomes including CSF leakage and reoperation rates
• Demonstrated high efficacy in sealing dural membranes
• Reduced risk of postoperative CSF leakage compared to previous methods
• Low rates of reoperation following application of Vivostat