Do beta-blockers improve endothelial function compared to placebo or other antihypertensive agents?
Beta-blockers, particularly third-generation agents, improve endothelial function compared to placebo, though their benefit is less than that of ACE inhibitors.
Beta-blockers improve the endothelial function compared with placebo. More-over, third generation beta-blockers improve FMD values significantly better than the second generation ones. Beta-blockers had similar effect on endothelial function as did ARB, CCB or diuretics. However, the beneficial effect of beta-blockers was lower when confronted with ACEI.
Peller et al. (Thu,) studied this question.