Spontaneous termination of paroxysmal AF is preceded by abrupt changes in fibrillatory wave frequency, which could potentially guide targeted pacing therapies.
Low frequency fibrillation was found to be much more likely to terminate. Frequency changes preceding spontaneous termination were abrupt, in contrast to the gradual frequency drop reported with drug-induced termination. The analysis of fibrillatory wave characteristics and their change over time might be used to target specific moments for pacing therapy in patients with AF.
Petrutiu et al. (Thu,) studied this question.