This research aims to assess the differences in effects of sacubitril-valsartan compared to valsartan in treating heart failure with preserved ejection fraction between genders.
Randomized trial (NCT01920711)
Involved both men and women with heart failure and preserved ejection fraction
Compared the effects of sacubitril-valsartan and valsartan
Sacubitril-valsartan showed improved outcomes in heart failure treatment compared to valsartan, particularly among women.
Specific metrics and statistical outcomes were analyzed to quantify this difference.