Objective: To evaluate the clinical, surgical, and pathological outcomes of patients who underwent transperitoneal laparoscopic adrenalectomy (LA) for adrenal masses in our department over the past 5 years. Material and Methods: We retrospectively reviewed 100 patients who underwent LA between December 2017-May 2024. Demographic data, perioperative parameters, complication rates, and pathological findings were analysed. Preoperative endocrine evaluation and radiological imaging were performed in all patients. Statistical analysis was conducted using SPSS v25.0, and significance was set at p<0.05. Results: The cohort included 65 females and 35 males, with a mean age of 54.1±13.5 years. Right-sided LA was more frequent (58%). The mean mass size was 43.7±23.6 mm, and the average operative time was 103.9±27.8 minutes. Conversion to open surgery occurred in 4 (4%) patients. Seven patients experienced Clavien-Dindo grade II complications requiring transfusion; no grade III-V complications or mortality were observed. Histopathology revealed 62 adenomas, 29 benign non-adenomatous lesions, and 9 malignancies, including 3 renal cell carcinoma metastases and 2 adrenocortical carcinomas. Functional adrenal masses were present in 61% of patients, with clinical improvement observed postoperatively. Conclusion: LA is a safe and effective minimally invasive approach for adrenal masses, offering favorable perioperative outcomes and low complication rates. Even in complex cases, including large tumors and pheochromocytomas, LA can be performed safely with appropriate patient selection and surgical expertise.
ÇOBAN et al. (Thu,) studied this question.