Stimulus‐Dependent, Not Resting‐State, Neural Dysfunction Underlies the Neurobiology of Delayed Ejaculation: A Task‐Based fMRI Investigation

Key Points

• The study investigates the neural basis of delayed ejaculation to identify dysfunction during stimuli rather than resting state.
• Utilized task-based fMRI to observe neural activity in response to specific stimuli.
• Analyzed connectivity within the sensorimotor network and parahippocampal gyrus (PHG).
• Measured brain responses during task performance to assess neural regulation related to ejaculation.
• Found major inhibition of the sensorimotor network associated with delayed ejaculation.
• Identified significant connectivity disruption centered on the PHG.
• Demonstrated that neural dysregulation is stimulus-dependent rather than due to resting-state abnormalities.