Does second-generation antipsychotic exposure during the first trimester increase the risk of major congenital malformations in pregnant women?
First-trimester exposure to second-generation antipsychotics is not associated with an increased risk of major congenital malformations, providing reassurance for pregnant women requiring these medications.
Conclusions: SGA exposure during the first trimester is not associated with an increased risk of major congenital malformations. These findings might be reassuring for pregnant women who require SGAs.
Yakuwa et al. (Thu,) studied this question.