July 24, 2019Open Access

Dolutegravir plus Two Different Prodrugs of Tenofovir to Treat HIV

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Abstract

Treatment with DTG combined with either of two tenofovir prodrugs (TAF and TDF) showed noninferior efficacy to treatment with the standard-care regimen. There was significantly more weight gain with the DTG-containing regimens, especially in combination with TAF, than with the standard-care regimen. (ADVANCE ClinicalTrials.gov number, NCT03122262.).

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Venter et al. (Wed,) studied this question.

synapsesocial.com/papers/69d73465447a5ff6a2b8a487 https://doi.org/https://doi.org/10.1056/nejmoa1902824

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