This narrative review highlights the gap between the established short-term benefits of dietary nitrate in laboratory settings and the lack of evidence for its long-term efficacy in improving population health.
The salutary effects of dietary NO3- are well established in small, well-controlled laboratory studies. Much less is known about the feasibility and efficacy of long-term dietary NO3- enrichment for promoting health, and the factors which might explain the variable responsiveness to dietary NO3- supplementation between individuals. Future research focussing on the translation of laboratory data will provide valuable insight into the potential applications of dietary NO3- supplementation to improve population health.
Shannon et al. (Mon,) studied this question.