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Scleral lens-induced central corneal edema is greater in post-penetrating keratoplasty eyes and varies regionally compared with healthy corneas after short-term wear. Lens design and fitting factors contributing to hypoxic and mechanical corneal stress should be carefully considered for all post-penetrating keratoplasty scleral lens fits to minimize potential graft rejection or failure in the longer-term.
Kumar et al. (Tue,) studied this question.
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