What question did this study set out to answer?

To assess the prognostic value of preoperative gallium-68 PSMA PET/CT in predicting biochemical recurrence (BCR) after radical prostatectomy.

April 10, 2026

Prognostic value of preoperative gallium-68 prostate-specific membrane antigen PET/computed tomography in predicting biochemical recurrence after radical prostatectomy

Key Points

To assess the prognostic value of preoperative gallium-68 PSMA PET/CT in predicting biochemical recurrence (BCR) after radical prostatectomy.
Analyzed intraprostatic SUVmax as a potential imaging biomarker
Evaluated correlation between SUVmax and BCR rates
Identified patient outcomes related to BCR-free survival
Higher intraprostatic SUVmax correlates with increased risk of BCR
Shorter BCR-free survival is associated with elevated SUVmax levels
Findings suggest SUVmax may not be a standalone prognostic factor but indicates the need for further validation.

Abstract

Intraprostatic SUVmax appears to be an exploratory imaging biomarker associated with postoperative BCR and shorter BCR-free survival rather than a stand-alone prognostic determinant. Larger prospective multicenter studies are needed for validation.

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Prognostic value of preoperative gallium-68 prostate-specific membrane antigen PET/computed tomography in predicting biochemical recurrence after radical prostatectomy

Key Points

Abstract

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