September 27, 2018Open Access

Celastrol ameliorates cisplatin nephrotoxicity by inhibiting NF-κB and improving mitochondrial function

Key Points

Key points are not available for this paper at this time.

Abstract

This work suggested that celastrol could protect against cisplatin-induced acute kidney injury possibly through suppressing NF-κB and improving mitochondrial function. FUND: The National Natural Science Foundation of China, National Key Research and Development Program, and Natural Science Foundation of Jiangsu Province.

Read Full Paperexternally

اسأل الذكاء الاصطناعي

Bookmark

View Full Paper

Cite This Study

Yu et al. (Thu,) studied this question.

synapsesocial.com/papers/69d8fb582c39562886ae3ab1 https://doi.org/https://doi.org/10.1016/j.ebiom.2018.09.031

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Chronic Inhibition of Cardiac Kir2.1 and hERG Potassium Channels by Celastrol with Dual Effects on Both Ion Conductivity and Protein Trafficking2006 · 87 citations
2PTPRO Promotes Oxidized Low-Density Lipoprotein Induced Oxidative Stress and Cell Apoptosis through Toll-Like Receptor 4/Nuclear Factor κB Pathway2017 · 37 citations
3Down-regulation of GRP78 alleviates lipopolysaccharide-induced acute kidney injury2018 · 23 citations
4Red Ginseng Ameliorates Acute Cisplatin-Induced Nephropathy2014 · 37 citations
5Treatment of Obesity with Celastrol2015 · 727 citations

اسأل الذكاء الاصطناعي

Bookmark

View Full Paper