A shotgun approach to identifying immune evading excipients for biologics drugs

Key Points

• The research aims to identify excipients that contribute to immune evasion in biologic drugs.
• Utilizing a shotgun approach to screen various excipients
• Assessing their effects on immune response
• Evaluating the performance of multiple formulations
• Identified specific excipients that evade immune detection
• Demonstrated variations in immune response based on excipient composition
• Proposed new formulations that enhance drug stability while minimizing immune interference