March 23, 2017Open Access

MHC class I chain-related protein A and B (MICA and MICB) are predominantly expressed intracellularly in tumour and normal tissue

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Abstract

This demonstrates for the first time that MICA/B is more broadly expressed in normal tissue and that expression is mainly intracellular with only a small fraction appearing on the cell surface of some epithelia and tumour cells.

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Ghadially et al. (Thu,) studied this question.

synapsesocial.com/papers/69da8b3f0f0ab7a47c8359a2 https://doi.org/https://doi.org/10.1038/bjc.2017.79

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