February 1, 2001

Evidence that neurones accumulating amyloid can undergo lysis to form amyloid plaques in Alzheimer's disease

MDM. R. D’AndreaUniversity of Aberdeen RNRobert G. NageleStratford University HWH‐Y WangChinese Academy of Agricultural Sciences

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Abstract

Our findings suggest that excessive intracellular accumulation of A beta 42-positive material in pyramidal cells can result in cell lysis, and that cell lysis is an important source of amyloid plaques and neuronal loss in AD brains.

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D’Andrea et al. (Thu,) studied this question.

synapsesocial.com/papers/69dab5660f32475823a3d9f0 https://doi.org/https://doi.org/10.1046/j.1365-2559.2001.01082.x

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