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Human Health Effects of Tetrachloroethylene: Key Findings and Scientific Issues | Synapse

February 14, 2014Open Access

Human Health Effects of Tetrachloroethylene: Key Findings and Scientific Issues

Key Points

Key points are not available for this paper at this time.

Abstract

PCE is likely to be carcinogenic to humans. Neurotoxicity is a sensitive adverse health effect of PCE.

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Guyton et al. (Fri,) studied this question.

synapsesocial.com/papers/69dbd4ee387cf70698688e45 https://doi.org/https://doi.org/10.1289/ehp.1307359

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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1[Tetrachloroethylene: effect of low concentrations of 1,1,2,2-tetrachloroethylene (perchloroethylene) on organisms in the mouse. I. Laboratory chemical research].1985 · 2 citations
2Studies of acute nephrotoxic potential of trichloroethylene in fischer 344 rats1988 · 13 citations
3NTP Carcinogenesis Studies of Trichloroethylene (Without Epichlorohydrin) (CAS No. 79-01-6) in F344/N Rats and B6C3F1 Mice (Gavage Studies).1990 · 42 citations
4Differential response to trichloroethylene-induced hepatosteatosis in wild-type and PPARα-humanized mice2010 · 2 citations
5Trichloroacetic acid: Updated estimates of its bioavailability and its contribution to trichloroethylene-induced mouse hepatomegaly2011 · 7 citations