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History and bedside examination are still fundamental to a correct diagnosis, whilst screening tools and questionnaires are useful in indicating probable NP; QST is also useful for indicating the latter, and to assess provoked pains and treatment response. Amongst laboratory tests, LEPs are the best tool for assessing Adelta pathway dysfunction, and skin biopsy for assessing neuropathies with distal loss of unmyelinated nerve fibres.
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G. Cruccu
Sapienza University of Rome
Claudia Sommer
University of North Carolina at Chapel Hill
Praveen Anand
Imperial College London
European Journal of Neurology
Inserm
Imperial College London
Heidelberg University
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Cruccu et al. (Mon,) studied this question.
synapsesocial.com/papers/69dbde28498b35d3e6a3d63f — DOI: https://doi.org/10.1111/j.1468-1331.2010.02969.x