January 21, 2017Open Access

Prevention of cardiac surgery-associated AKI by implementing the KDIGO guidelines in high risk patients identified by biomarkers: the PrevAKI randomized controlled trial

Structured PICO

Does the implementation of KDIGO guidelines reduce the frequency and severity of AKI in biomarker-identified high-risk patients undergoing cardiac surgery?

Population

High risk patients identified by biomarkers undergoing cardiac surgery

Intervention

Implementation of the KDIGO guidelines

Comparator

Standard care

Outcome

Frequency and severity of acute kidney injury (AKI)hard clinical

Implementing KDIGO guidelines in biomarker-identified high-risk patients reduces the frequency and severity of AKI after cardiac surgery.

Abstract

An implementation of the KDIGO guidelines compared with standard care reduced the frequency and severity of AKI after cardiac surgery in high risk patients. Adequately powered multicenter trials are warranted to examine mortality and long-term renal outcomes.

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