Sacubitril/valsartan attenuates hypoxia/reoxygenation-induced cardiomyocyte injury by promoting M2 macrophage polarization and reducing TLR4/NF-κB signaling.
Sacubitril/valsartan demonstrates protective effects against hypoxia/reoxygenation-induced cardiomyocyte injury in vitro through modulation of macrophage polarization and the TLR4/NF-κB pathway.
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Sac/Val attenuates H/R-triggered AC16 cell injury by promoting M2 macrophage polarization, associated with attenuated TLR4/NF-κB signaling.
Jin et al. (Sun,) reported a other. Sacubitril/valsartan attenuates hypoxia/reoxygenation-induced cardiomyocyte injury by promoting M2 macrophage polarization and reducing TLR4/NF-κB signaling.