Does cardiovascular risk increase the risk of depressive symptoms during the first 18 years of life?
Higher cardiovascular risk in childhood and adolescence increases the risk of developing depressive symptoms, potentially mediated by childhood inflammation.
Association between CVD risk and depression in childhood/adolescence is unidirectional, with higher CVD risk increasing the risk of depressive symptoms. Childhood inflammation may increase risk of depression by influencing adolescent CVD risk.
Chaplin et al. (Wed,) studied this question.
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