Receptor-Interacting Protein Kinase 3 Contributes to Abdominal Aortic Aneurysms via Smooth Muscle Cell Necrosis and Inflammation

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Abstract

Enhanced RIP3 signaling in aneurysmal tissues contributes to AAA progression by causing SMC necroptosis, as well as stimulating vascular inflammation, and therefore may serve as a novel therapeutic target for AAA treatment.

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Wang et al. (Wed,) studied this question.

synapsesocial.com/papers/69de84bfbf539e2270558e29 https://doi.org/https://doi.org/10.1161/circresaha.116.304899

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