Azelaic acid-integrated therapeutic deep eutectic systems: overcoming solubility and permeability barriers for enhanced transdermal drug delivery

Key Points

• The research aims to enhance the transdermal delivery of azelaic acid by integrating it into therapeutic deep eutectic systems.
• Developed therapeutic deep eutectic systems with azelaic acid
• Analyzed the solubility and permeability of the formulations
• Conducted comparative assessments of transdermal delivery efficacy
• Significantly improved solubility of azelaic acid in the developed systems
• Enhanced permeability barriers led to increased drug absorption
• Demonstrated effective transdermal delivery for skin disorders

Abstract