Methodological approaches for estimating radiosensitivity in Quillaja saponaria : comparison of LD 50 models and a PCA-based integrative index

Key Points

• The study aims to evaluate the effectiveness of multivariate integration methods for estimating radiosensitivity in Quillaja saponaria.
• Utilized growth-based multivariate integration techniques
• Compared LD50 models with a PCA-based approach
• Assessed radiosensitivity in response to ionizing radiation
• PCA provides a robust integrative estimator for radiosensitivity
• Growth-based methods show a stronger biological relevance than binary endpoints
• PCA may serve as a reference threshold for future research in woody species