Predictors of Recurrence in Human Papillomavirus‐Associated Oropharyngeal Squamous Cell Carcinoma

Key Points

• This research aims to identify factors that predict recurrence in HPV-associated oropharyngeal squamous cell carcinoma.
• Analyzed recurrence and survival patterns in patients with HPV+ OPSCC
• Assessed the role of perineural invasion in recurrence
• Examined individual surveillance approaches based on patient characteristics
• Distinct patterns of recurrence and survival were observed in HPV+ OPSCC patients
• Perineural invasion was identified as a significant predictor of recurrence
• Current findings support the need for more personalized surveillance strategies for these patients