DBU Mediated Thiocyanate and Selenocyanate Activation Enables Transition-Metal-Free Synthesis of Chalcogen-Linked Heterocycles

Key Points

• To establish a protocol for synthesizing chalcogen-linked organosulfur and organoselenium frameworks without using transition metals.
• DBU mediated coupling of heteroaryl thiocyanates and selenocyanates with alkyl halides
• Synthesis of organosulfur and organoselenium frameworks
• Use of pseudohalides in the reaction
• Successfully synthesized various chalcogen-linked heterocycles
• Avoided the need for transition metals in the synthesis
• Demonstrated efficiency in using alkyl halides and pseudohalides