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This research investigates the impact of 5-Hz TMS on cognitive function in stroke recovery individuals.

April 17, 2026Open Access

Efficacy of 5‐Hz Transcranial Magnetic Stimulation Over the Left Dorsolateral Prefrontal Cortex in Improving Cognitive Function During the Recovery Phase of Stroke

Key Points

This research investigates the impact of 5-Hz TMS on cognitive function in stroke recovery individuals.
Applied 5-Hz TMS to the left dorsolateral prefrontal cortex (DLPFC) in stroke patients.
Assessed cognitive function improvements post-stimulation.
Compared effects of stimulation with and without ipsilateral lesions.
5-Hz TMS significantly enhances cognitive functioning in stroke recovery patients.
Effects of stimulation are comparable regardless of lesion location relative to the DLPFC.

Abstract

High-frequency (5 Hz) TMS applied to the left DLPFC significantly enhances overall cognitive functioning in patients who are recovering from strokes. Interestingly, we found that when 5-Hz TMS was applied to the left DLPFC, its effects were similar regardless of whether the lesion was ipsilateral to the stimulation site or not.

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