Female-Biased VSMC GRNs Predict MYH9 as Regulator of Fibrous Plaque Phenotype | Synapse
April 17, 2026
Female-Biased VSMC GRNs Predict MYH9 as Regulator of Fibrous Plaque Phenotype
Key Points
The aim is to explore the role of MYH9 in regulating fibrous plaques with a focus on sex differences.
Analysis of gene regulatory networks (GRNs) related to vascular smooth muscle cells (VSMC).
Investigation of MYH9's role in fibrous plaque formation in atherosclerosis.
MYH9 emerges as a significant regulator in female-biased fibrous plaque biology.
The study highlights the importance of sex-specific differences in atherosclerosis.
Abstract
These findings identify MYH9 as a regulator of female-biased fibrous plaque biology and highlight the importance of sex-specific network regulation in atherosclerosis.