Assessment of Mitochondrial DNA Copy Number in Progressive Supranuclear Palsy Patients: Evidence From a Pilot Study

Key Points

• The aim is to explore the role of mitochondrial DNA copy number in the pathogenesis of progressive supranuclear palsy (PSP).
• Assess mitochondrial DNA copy number in PSP patients
• Analyze the correlation with disease progression
• Non-invasive data collection methods
• Mitochondrial dysfunction is evident in PSP patients
• Peripheral mtDNA copy number may serve as a useful biomarker
• Further research is needed in larger cohorts for validation