What question did this study set out to answer?

To highlight the radiological findings and diagnostic challenges associated with adenosquamous carcinoma of the liver.

April 20, 2026Open Access

A rare variant of primary hepatic tumors; Adenosquamous carcinoma; radiological findings

Key Points

To highlight the radiological findings and diagnostic challenges associated with adenosquamous carcinoma of the liver.
Reported a case of a 56-year-old woman with epigastric pain.
Discussed the radiological challenges faced during diagnosis.
Reviewed existing literature on primary hepatic adenosquamous carcinoma.
Identified adenosquamous carcinoma as a rare subtype of cholangiocarcinoma.
Noted significant diagnostic problems in radiology due to the tumor's unique features.

Abstract

Adenosquamous carcinoma of the liver (ASC) is considered a very rare subtype of cholangiocarcinoma. The definition of ASC indicates a carcinoma including both adenocarcinoma and squamous carcinoma components. Knowledge about primary hepatic ASC is limited to case reports. It reveals diagnostic problems in radiology practice. In this case report, we represented a 56-year-old woman who was admitted to the hospital with a complaint of epigastric pain for three months.

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